BUTANOL-EXTRACTABLE IODINE OF SERUM 1

Butanol-extractable iodine of serum.

It has been demonstrated chemically that the iodine bound to proteins of the serum is predominantly composed of thyroxine (1-4). The concentration of this protein-bound or serum precipitable iodine (SPI) appears to be closely correlated with the activity of the thyroid gland (5-7). It is probably the most precise clinical criterion of such activity that has yet been extensively employed. It is,...

Normal Range of Serum Butanol-Extractable Iodine of Human Adults *

In the diagnosis of masked hyperthyroidism, measurement of the serum precipitable iodine (SPI) (frequently also called protein-bound iodine [PBI]) has gained significance. Since 1951 determination of thyroxine-like or butanol-extractable iodine (BEI) has been the routine procedure in this laboratory.' This chemical tool is more specific than the PBI in the diagnosis of thyroid dysfunction. Not ...

A simplified method for butanol-extractable iodine and butanol-insoluble iodine.

A simplified method is presented for the determination of butanol-extractable iodine (BEI). The results compare favorably with the original method as described by Man et al. Also available, as part of the procedure for BEI, is a direct chemical determination for butanol-insoluble iodine (Bli) from the same specimen of serum. Heretofore, nonbutanol-extractable iodine has been studied only by mea...

Serum Butanol-Extractable Iodines in Abortions ‡

Butanol-extractable iodine in human and bovine colostrum and milk.

High total iodine content and significant amounts of iodinated amino acids, but not of thyronines, have been reported in milk of various species. Since the human neonate requires thyroxine-like iodine compounds for central nervous system development, analyses of thyroxine-like iodine compounds such as butanol-extractable iodine of colostrum or early milk were indicated. Four samples of human mi...